利用MATLAB程序中的inline和nlinfit两个命令对血药浓度-时间数据进行非线性拟合,求解血管外给药的药动学参数。同时与3P97软件计算结果进行了比较,结果表明,基于MATLAB程序可方便快速地求解血管外给药的各个药动学参数,计算结果与3P97软件计算值相当,且本方法操作简便、界面直观、易于推广,可用于临床教学或实验中药动学参数的计算。 更多还原-Using MATLAB program inline and nlinfit two commands to the plasma concentration- time data by nonlinear fitting, solving the pharmacokinetic parameters of extravascular administration. Simultaneously with the 3P97 software to calculate the results were compared, the results show that can quickly and easily solve extravascular administration of various pharmacokinetic parameters based on MATLAB, the results calculated with 3P97 software fairly, and that the method is simple, intuitive interface, easy to spread, can be used to calculate the clinical teaching or experimental medicine pharmacokinetic parameters. More Restore