The presence of different energy carriers as well as the advent of new multi-generation technologies such as combined heat and power (CHP) at homes necessitates designing an integrated model for optimal operation of such multi-carrier energy home. A residential energy hub model including a CHP and a Plug-in hybrid electric vehicle (PHEV) is presented in this paper to show the multi-carrier energy system operation. In addition, this paper proposes an optimization-based formulation for PHEV charging control in the residential energy hub. The payment cost is minimized for the charge scheduling of PHEV through optimization of the residential energy hub operation in response to the time-differentiated pricing of electricity.